The antibacterial effect against Escherichia coli and the cytotoxic activities against mouse calvaria derived cell line (MC 3T3-E1) was studied for copper- and zinc-doped silicon oxide films grown by atmospheric pressure chemical vapour deposition. The antibacterial effect of the films is related to the formation of copper and zinc oxide particles, homogeneously distributed on the film surface. The bacteria are killed already within the first three hours after exposure to the antiseptic particles. The higher release of copper or zinc in the first days inhibited also cell growth, which is less pronounced in the initial stage of the test. The obtained results indicate that the films have a high potential to be used as effective antibacterial films in medical applications.
| Date of Award | 2014 |
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| Original language | English |
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| Awarding Institution | |
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| Supervisor | Christian Mitterer (Supervisor) & Jürgen Schmidt (Supervisor) |
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Antibacterial films for medical applications grown by atmospheric pressure plasma deposition
Irauschek, E. (Author). 2014
Student thesis: Master's Thesis