New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics

Markus Zeilinger; Florian Pichler; Lukas Nics; Wolfgang Wadsak; Helmut Spreitzer; Marcus Hacker; Markus Mitterhauser

doi:10.1186/s13550-016-0249-9

New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics

Markus Zeilinger
, Florian Pichler
, Lukas Nics
, Wolfgang Wadsak
, Helmut Spreitzer
, Marcus Hacker
, Markus Mitterhauser

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	22
Journal	EJNMMI Research
Volume	7
Issue number	1
DOIs	https://doi.org/10.1186/s13550-016-0249-9
Publication status	Published - 1 Dec 2017

Keywords

AR
Binding affinity
Binding kinetics
Cell-based ligand interaction analysis
Kinetic competition assay
Real-time cell-binding studies

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10.1186/s13550-016-0249-9

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title = "New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics",

keywords = "AR, Binding affinity, Binding kinetics, Cell-based ligand interaction analysis, Kinetic competition assay, Real-time cell-binding studies",

author = "Markus Zeilinger and Florian Pichler and Lukas Nics and Wolfgang Wadsak and Helmut Spreitzer and Marcus Hacker and Markus Mitterhauser",

note = "Publisher Copyright: {\textcopyright} 2017, The Author(s).",

year = "2017",

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day = "1",

doi = "10.1186/s13550-016-0249-9",

language = "English",

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T1 - New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics

AU - Zeilinger, Markus

AU - Pichler, Florian

AU - Nics, Lukas

AU - Wadsak, Wolfgang

AU - Spreitzer, Helmut

AU - Hacker, Marcus

AU - Mitterhauser, Markus

PY - 2017/12/1

Y1 - 2017/12/1

KW - AR

KW - Binding affinity

KW - Binding kinetics

KW - Cell-based ligand interaction analysis

KW - Kinetic competition assay

KW - Real-time cell-binding studies

UR - https://www.scopus.com/pages/publications/85014894098

U2 - 10.1186/s13550-016-0249-9

DO - 10.1186/s13550-016-0249-9

M3 - Article

AN - SCOPUS:85014894098

SN - 2191-219X

VL - 7

JO - EJNMMI Research

JF - EJNMMI Research

IS - 1

M1 - 22

ER -

New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics

Keywords

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