Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment

Sabine Leitner; Aida Abdel Gelil; Markus Zeilinger; Lukas Zimmermann; Monika Clausen; Dietmar Georg; Barbara Knäusl

Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment

Sabine Leitner, Aida Abdel Gelil, Markus Zeilinger, Lukas Zimmermann, Monika Clausen, Dietmar Georg, Barbara Knäusl

Research output: Contribution to conference › Poster › peer-review

Abstract

The establishment of a standardized micro-CT imaging workflow which enables reliable and reproducible results are essential in small-animal irradiation. Image quality and a consistent quantitative micro-CT imaging read-out are central prerequisites for treatment planning, dosimetrical considerations, appropriate immobilization, position verification and treatment response assessment in pre-clinical irradiation research. In line with that the impact of acquisition and reconstruction parameters on the dedicated image-read out, has to be evaluated and optimized. This project aimed at the verification and validation of micro-CT imaging data by means of quantitative evaluation and assessment of Hounsfield units (HU) and image quality and how they are influenced by a set of different acquisition and reconstruction parameters.

Original language	English
Publication status	Published - 21 Mar 2022
Event	5th Conference on small animal precision image-guided radiotherapy: SAPIR - München, München, Germany Duration: 21 Mar 2022 → 23 Mar 2022 https://www.efomp.org/index.php?r=events/view&id=175

Conference

Conference	5th Conference on small animal precision image-guided radiotherapy
Abbreviated title	SAPIR
Country/Territory	Germany
City	München
Period	21/03/22 → 23/03/22
Internet address	https://www.efomp.org/index.php?r=events/view&id=175

Cite this

Leitner, S., Abdel Gelil, A., Zeilinger, M., Zimmermann, L., Clausen, M., Georg, D., & Knäusl, B. (2022). Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment. Poster session presented at 5th Conference on small animal precision image-guided radiotherapy, München, Germany.

Leitner, Sabine ; Abdel Gelil, Aida ; Zeilinger, Markus et al. / Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment. Poster session presented at 5th Conference on small animal precision image-guided radiotherapy, München, Germany.

@conference{1eb34e8ebd714655b3c7ba188a44591a,

title = "Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment",

abstract = "The establishment of a standardized micro-CT imaging workflow which enables reliable and reproducible results are essential in small-animal irradiation. Image quality and a consistent quantitative micro-CT imaging read-out are central prerequisites for treatment planning, dosimetrical considerations, appropriate immobilization, position verification and treatment response assessment in pre-clinical irradiation research. In line with that the impact of acquisition and reconstruction parameters on the dedicated image-read out, has to be evaluated and optimized. This project aimed at the verification and validation of micro-CT imaging data by means of quantitative evaluation and assessment of Hounsfield units (HU) and image quality and how they are influenced by a set of different acquisition and reconstruction parameters. ",

author = "Sabine Leitner and {Abdel Gelil}, Aida and Markus Zeilinger and Lukas Zimmermann and Monika Clausen and Dietmar Georg and Barbara Kn{\"a}usl",

year = "2022",

month = mar,

day = "21",

language = "English",

note = "5th Conference on small animal precision image-guided radiotherapy ; Conference date: 21-03-2022 Through 23-03-2022",

url = "https://www.efomp.org/index.php?r=events/view&id=175",

}

Leitner, S, Abdel Gelil, A, Zeilinger, M, Zimmermann, L, Clausen, M, Georg, D & Knäusl, B 2022, 'Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment', 5th Conference on small animal precision image-guided radiotherapy, München, Germany, 21/03/22 - 23/03/22.

Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment. / Leitner, Sabine; Abdel Gelil, Aida; Zeilinger, Markus et al.
2022. Poster session presented at 5th Conference on small animal precision image-guided radiotherapy, München, Germany.

Research output: Contribution to conference › Poster › peer-review

TY - CONF

T1 - Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment

AU - Leitner, Sabine

AU - Abdel Gelil, Aida

AU - Zeilinger, Markus

AU - Zimmermann, Lukas

AU - Clausen, Monika

AU - Georg, Dietmar

AU - Knäusl, Barbara

PY - 2022/3/21

Y1 - 2022/3/21

N2 - The establishment of a standardized micro-CT imaging workflow which enables reliable and reproducible results are essential in small-animal irradiation. Image quality and a consistent quantitative micro-CT imaging read-out are central prerequisites for treatment planning, dosimetrical considerations, appropriate immobilization, position verification and treatment response assessment in pre-clinical irradiation research. In line with that the impact of acquisition and reconstruction parameters on the dedicated image-read out, has to be evaluated and optimized. This project aimed at the verification and validation of micro-CT imaging data by means of quantitative evaluation and assessment of Hounsfield units (HU) and image quality and how they are influenced by a set of different acquisition and reconstruction parameters.

AB - The establishment of a standardized micro-CT imaging workflow which enables reliable and reproducible results are essential in small-animal irradiation. Image quality and a consistent quantitative micro-CT imaging read-out are central prerequisites for treatment planning, dosimetrical considerations, appropriate immobilization, position verification and treatment response assessment in pre-clinical irradiation research. In line with that the impact of acquisition and reconstruction parameters on the dedicated image-read out, has to be evaluated and optimized. This project aimed at the verification and validation of micro-CT imaging data by means of quantitative evaluation and assessment of Hounsfield units (HU) and image quality and how they are influenced by a set of different acquisition and reconstruction parameters.

M3 - Poster

T2 - 5th Conference on small animal precision image-guided radiotherapy

Y2 - 21 March 2022 through 23 March 2022

ER -

Leitner S, Abdel Gelil A, Zeilinger M, Zimmermann L, Clausen M, Georg D et al.. Evaluation, validation and quantitative assessment of a small-animal computed tomography imaging system for the central implementation of image-guided treatment planning, irradiation and response assessment. 2022. Poster session presented at 5th Conference on small animal precision image-guided radiotherapy, München, Germany.