Dose determination and verification of a small-animal spiral micro computed tomography system for preclinical in vivo imaging

Sabine Leitner; Markus Zeilinger; Dietmar Georg; Claudia Schmidt; Monika Clausen

Dose determination and verification of a small-animal spiral micro computed tomography system for preclinical in vivo imaging

Sabine Leitner, Markus Zeilinger, Dietmar Georg, Claudia Schmidt, Monika Clausen

Research output: Contribution to conference › Poster › peer-review

Abstract

The radiation dose delivered to an animal during a cone-beam shaped micro-Computed Tomography (micro-CT) is not negligible and might contribute to animal discomfort, as well as lead to undesired biological effects. Especially in cancer research high doses of ionizing radiation may interfere with the respective study objectives and alter the experimental outcome [1]. The aim of this study was to verify the estimated calculated dose values given by the vendor of a newly implemented micro-CT for further preclinical in vivo imaging.

Original language	English
Publication status	Published - 15 Mar 2024
Event	EMIM - European Molecular Imaging Meeting - Duration: 12 Mar 2024 → 15 Mar 2024

Conference

Conference	EMIM - European Molecular Imaging Meeting
Abbreviated title	EMIM
Period	12/03/24 → 15/03/24

Cite this

@conference{1f85a253b58d4a03abe5d490ff880f08,

title = "Dose determination and verification of a small-animal spiral micro computed tomography system for preclinical in vivo imaging",

abstract = "The radiation dose delivered to an animal during a cone-beam shaped micro-Computed Tomography (micro-CT) is not negligible and might contribute to animal discomfort, as well as lead to undesired biological effects. Especially in cancer research high doses of ionizing radiation may interfere with the respective study objectives and alter the experimental outcome [1]. The aim of this study was to verify the estimated calculated dose values given by the vendor of a newly implemented micro-CT for further preclinical in vivo imaging.",

author = "Sabine Leitner and Markus Zeilinger and Dietmar Georg and Claudia Schmidt and Monika Clausen",

year = "2024",

month = mar,

day = "15",

language = "English",

note = "EMIM - European Molecular Imaging Meeting, EMIM ; Conference date: 12-03-2024 Through 15-03-2024",

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TY - CONF

T1 - Dose determination and verification of a small-animal spiral micro computed tomography system for preclinical in vivo imaging

AU - Leitner, Sabine

AU - Zeilinger, Markus

AU - Georg, Dietmar

AU - Schmidt, Claudia

AU - Clausen, Monika

PY - 2024/3/15

Y1 - 2024/3/15

N2 - The radiation dose delivered to an animal during a cone-beam shaped micro-Computed Tomography (micro-CT) is not negligible and might contribute to animal discomfort, as well as lead to undesired biological effects. Especially in cancer research high doses of ionizing radiation may interfere with the respective study objectives and alter the experimental outcome [1]. The aim of this study was to verify the estimated calculated dose values given by the vendor of a newly implemented micro-CT for further preclinical in vivo imaging.

AB - The radiation dose delivered to an animal during a cone-beam shaped micro-Computed Tomography (micro-CT) is not negligible and might contribute to animal discomfort, as well as lead to undesired biological effects. Especially in cancer research high doses of ionizing radiation may interfere with the respective study objectives and alter the experimental outcome [1]. The aim of this study was to verify the estimated calculated dose values given by the vendor of a newly implemented micro-CT for further preclinical in vivo imaging.

M3 - Poster

T2 - EMIM - European Molecular Imaging Meeting

Y2 - 12 March 2024 through 15 March 2024

ER -