Real-time motion and retrospective receiver sensitivity correction for gluCEST using volumetric navigators (vNavs) at 7T

CEST is susceptible to subject motion not only due to misregistration of MR images acquired over time and subsequent alterations of B0 field, but also due to the related receiver sensitivity (B1-) inhomogeneities. We propose to correct for ∆B1- from the images generated by an interleaved EPI navigator used for prospective motion correction. We show the benefit of the proposed method, in combination with B1+ and dynamic B0 corrections, to restore a glutamate weighted CEST map in an active healthy volunteer.